1. • General systemic disorders (e.g., erythroblastosis fetalis, hyperthyroidism, cretinism, intracranial masses, toxemia of pregnancy, prematurity) Preventive Measures

2. Specimens of placenta tissue from 39 normal and 31 pathological pregnancies (diabetes mellitus, toxemia, erythroblastosis and hydatiform mole) were incubated with tritiated thymidine.

3. While cases of severe erythroblastosis showed a statistically significant elevation of the HCG concentration in the amniotic fluid, in cord blood of newborns an increased content of HCG could not be proved statistically.

4. Athetosis A neurological disorder featuring involuntary, slow writhing movements of the hands, arms, face and tongue caused by a form of CEREBRAL PALSY. The commonest causes are ERYTHROBLASTOSIS FETALIS from rhesus incompatibility and brain lack of oxygen during birth.

5. Abnormalities can range from anatomical associated with degree or site of inplantation, structure (as with twinning), to placental function, placento-maternal effects (pre-eclampsia, fetal erythroblastosis) and finally mechanical Abnormalities associated with the placental (umbilical) cord.

6. According to their frequency, they appear to correlate with certain diseases (table 3), but none of the changes are specific for a certain disease: Perinuclear vacuoles, acidophilic fibers and acidophilic necroses very often exist with pulmonary diseases, with general infections and erythroblastosis.